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CRISPR/Cas9-Based Deletion of SpvB Gene From Salmonella gallinarum Leads to Loss of Virulence in Chicken

Salmonella Gallinarum causes fowl typhoid in poultry leading to a huge economic loss to the poultry industry. The large virulence plasmid of S. gallinarum has been associated with various systemic infections in poultry. A five-gene spanning region (spvRABCD) of 7.8 kb on the large plasmid mainly con...

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Principais autores: Abdul Basit, Hamza Tahir, Zulquernain Haider, Hafsa Tariq, Asim Ullah, Shafiq Ur Rehman
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fbioe.2022.885227/full
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