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Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies

In vivo imaging of biological processes is an important asset of modern cell biology. Selectively reacting fluorophores herein are an important tool and click chemistry reactions take a large share in these events. 5-Ethynyl-2′-deoxyuridine (EdU) is well known for visualizing DNA replication,...

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Principais autores: Akkaladevi Venkatesham, Sambasiva Rao Pillalamarri, Flore De Wit, Eveline Lescrinier, Zeger Debyser, Arthur Van Aerschot
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-01-01
Serier:Molecules
Fag:
click reaction
propargylated nucleosides
imaging
DNA visualization
fluorophores
ethynyl-2′-deoxyuridine (EdU)
HIV toxicity
Mitsunobu reaction
Online adgang:https://www.mdpi.com/1420-3049/24/3/468
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