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Characterization of a novel assay for full-length endotrophin in heart failure with preserved ejection fraction

Abstract Endotrophin is a matrikine released from the C-terminus of the alpha-3 chain of type VI collagen, gaining increasing attention both as a biomarker and as a therapeutic target in the cardiometabolic space. So far, it has been quantified in circulation by the PRO-C6 assay, which detects diffe...

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Principais autores: Elisavet Angeli, Elena Revuelta-López, Begoña López, Mathilde Raaholt Christensen, Shu Sun, Morten Karsdal, Federica Genovese, Arantxa González, Antoni Bayes-Genis
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-03-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-026-40557-9
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