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The effect of tauroursodeoxycholic Acid (TUDCA) treatment on placental endoplasmic reticulum (ER) stress in a rat model of advanced maternal age.

Advanced maternal age (≥35 years) is associated with an increased risk of pregnancy complications such as fetal growth restriction and preeclampsia. We previously demonstrated poor pregnancy outcomes (reduced fetal body weight), altered vascular function, and increased expression of endoplasmic reti...

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Principais autores: Mazhar Pasha, Raven Kirschenman, Amy Wooldridge, Floor Spaans, Christy-Lynn M Cooke, Sandra T Davidge
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2023-01-01
叢編:PLoS ONE
在線閱讀:https://doi.org/10.1371/journal.pone.0282442
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