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Neutralizing antibody levels detected early after mRNA-based vaccination do not predict by themselves subsequent breakthrough infections of SARS-CoV-2

The development of mRNA vaccines represented a significant achievement in response to the global health crisis during the SARS-CoV-2 pandemic. Evaluating vaccine efficacy entails identifying different anti-SARS-CoV-2 antibodies, such as total antibodies against the Receptor Binding Domain (RBD) of t...

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Autori principali: Roberto Alonso, Sergio Gil-Manso, Pilar Catalán, Ignacio Sánchez-Arcilla, Marco Marzola, Rafael Correa-Rocha, Patricia Muñoz, Marjorie Pion, the Gregorio Marañón Microbiology-ID COVID-19 Study Group
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-02-01
Serie:Frontiers in Immunology
Soggetti:
SARS-CoV-2
anti-RBD IgG
neutralizing antibodies
breakthrough infection
humoral immunity
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1341313/full
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