Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2−/− lipodystrophic mice independent of hepatocyte leptin receptors[S]

Leptin is essential for energy homeostasis and regulation of food intake. Patients with congenital generalized lipodystrophy (CGL) due to mutations in 1-acylglycerol-3-phosphate-O-acyltransferase 2 (AGPAT2) and the CGL murine model (Agpat2−/− mice) both have severe insulin resistance, diabetes melli...

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Podrobná bibliografie

Hlavní autoři:	Víctor A. Cortés, Kelly M. Cautivo, Shunxing Rong, Abhimanyu Garg, Jay D. Horton, Anil K. Agarwal
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2014-02-01
Edice:	Journal of Lipid Research
Témata:	acyltransferase phospholipids diabetes mellitus
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0022227520350355
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