High VCP/p97 expression associates with low PD-L1 TPS in oropharyngeal squamous cell carcinoma

Abstract Objectives VCP/p97 inhibition is known to upregulate PD-L1. This study investigated the correlation between PD-L1 and VCP/p97 expression in OPSCC, as well as the expression and prognostic significance of VCP/p97 in OPSCC. Methods The study retrospectively included 56 patients with OPSCC. Im...

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Hlavní autoři:	Inga Marte Charlott Seuthe, Markus Ruwe, Franz Mitze, Steffi Silling, Eric Ehrke-Schulz, Sabine Eichhorn, Jonas Jae-Hyun Park
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-10-01
Edice:	Discover Oncology
Témata:	PD-L1 VCP OPSCC HNSCC TILS
On-line přístup:	https://doi.org/10.1007/s12672-025-03839-8
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