Gonadotropin-releasing hormone-like receptor 2 inversely regulates somatic proteostasis and reproduction in Caenorhabditis elegans

The quality control machinery regulates the cellular proteome to ensure proper protein homeostasis (proteostasis). In Caenorhabditis elegans, quality control networks are downregulated cell-nonautonomously by the gonadal longevity pathway or metabolic signaling at the onset of reproduction. However,...

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Главные авторы:	Mor Kishner, Libat Habaz, Lana Meshnik, Tomer Dvir Meidan, Alexandra Polonsky, Anat Ben-Zvi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2022-08-01
Серии:	Frontiers in Cell and Developmental Biology
Предметы:	aging gonadal longevity signaling gonadotropin-releasing hormone (GnRH/GnRH receptor) proteostasis stress response reproduction
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fcell.2022.951199/full
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