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Facile quantitative diagnostic testing for neutralizing antibodies against Chikungunya virus

Abstract Background Viral neutralization (NT) assays can be used to determine the immune status of patients or assess the potency of candidate vaccines or therapeutic monoclonal antibodies (mAbs). Focus reduction neutralization test (FRNT) is a conventional neutralization test (cVNT) with superior s...

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Autori principali: Hui-Chung Lin, Shu-Fen Chang, Chien-Ling Su, Huai-Chin Hu, Der-Jiang Chiao, Yu-Lin Hsu, Hsuan-ying Lu, Chang-Chi Lin, Pei-Yun Shu, Szu-Cheng Kuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-09-01
Serie:BMC Infectious Diseases
Soggetti:
Chikungunya virus
Virus-like replicon particle
Neutralizing antibodies
Surrogate virus neutralization test
Surveillance
Diagnostics
Accesso online:https://doi.org/10.1186/s12879-024-09973-y
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