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Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been reported: the balance among disease resolution, an a...

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Principais autores: Zahra Khalajzeyqami, Andrea Grandi, Erica Ferrini, Francesca Ravanetti, Ludovica Leo, Martina Mambrini, Luciana Giardino, Gino Villetti, Franco Fabio Stellari
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2022-01-01
Serier:PLoS ONE
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200302/?tool=EBI
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