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Mycobacterium leprae downregulates the expression of PHEX in Schwann cells and osteoblasts

Neuropathy and bone deformities, lifelong sequelae of leprosy that persist after treatment, result in significant impairment to patients and compromise their social rehabilitation. Phosphate-regulating gene with homologies to endopeptidase on the X chromosome (PHEX) is a Zn-metalloendopeptidase, whi...

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Auteurs principaux: Sandra R Boiça Silva, Antônio J Tempone, Tatiana P Silva, Maria Renata SN Costa, Geraldo MB Pereira, Flávio A Lara, Maria Cristina V Pessolani, Danuza Esquenazi
Format: Artigo
Langue:Inglês
Publié: Fundação Oswaldo Cruz (FIOCRUZ) 2010-08-01
Collection:Memorias do Instituto Oswaldo Cruz
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Accès en ligne:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000500005
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