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Polarized Light Microscopy-Based Quantification of Scleral Collagen Fiber Bundle Remodeling in the Lens-Induced Myopia Mouse Model

Scleral remodeling plays a crucial role in myopia development. Although ultrastructural collagen changes have been described, quantitative assessment at the fiber bundle level remains limited. This study quantitatively evaluated scleral collagen remodeling in a lens-induced myopia (LIM) mouse model...

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Principais autores: Yajing Yang, Shin-ichi Ikeda, Longdan Kang, Ziyan Ma, Kazuno Negishi, Kazuo Tsubota, Yohei Tomita, Kate Gettinger, Toshihide Kurihara
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-11-01
Serier:Life
Fag:
collagen fiber bundles
polarized light microscopy
picrosirius red staining
scleral remodeling
myopia
Online adgang:https://www.mdpi.com/2075-1729/15/11/1743
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