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Cognitive and intellectual functioning in leukodystrophy patients: a systematic review

Abstract Background ‘Leukodystrophies’ encompass a group of genetic disorders affecting brain white matter, mostly characterized by neurological deterioration. Manifestations include mood changes, cognitive decline, motor dysfunction, and often early death. Underestimation of the cognitive decline m...

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Autori principali: Wietske H. M. Grol, Marjo S. van der Knaap, Nicole I. Wolf, Gert J. Geurtsen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-11-01
Serie:Orphanet Journal of Rare Diseases
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Accesso online:https://doi.org/10.1186/s13023-025-04083-7
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