ATM‐Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions

Abstract Repair of DNA double‐strand breaks (DSBs) is essential for genome integrity, and is accompanied by transcriptional repression at the DSB regions. However, the mechanisms how DNA repair induces transcriptional inhibition remain elusive. Here, it is identified that BRD7 participates in DNA da...

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Автори:	Kaishun Hu, Yu Li, Wenjing Wu, Limin Xie, Haiyan Yan, Yuexin Cai, Dong Chen, Qiongchao Jiang, Lehang Lin, Zhen Chen, Jian‐You Liao, Yin Zhang, H. Phillip Koeffler, Dong Yin, Erwei Song
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Wiley 2020-10-01
Серія:	Advanced Science
Предмети:	ATM BRD7 NuRD PRC2 transcriptional repression
Онлайн доступ:	https://doi.org/10.1002/advs.202000157
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