Screening and identification of novel anti-inflammatory peptides from sea cucumber gonads: In silico and in vitro analysis

This study identified three novel anti-inflammatory peptides from sea cucumber gonad hydrolysates: GDRGF, FDGPEGPRGPPGSEGRQG, and PSNLGTGLR. In vitro experiments demonstrated that these peptides, at concentrations ranging from 25 to 400 μg/mL, exhibited no cytotoxicity toward RAW264.7 macrophages an...

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Autori principali:	Zhiqin Zhang, Yongke Deng, Jingxuan Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Haimei Liu, Qin Zhao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-02-01
Serie:	Food Chemistry: X
Soggetti:	Sea cucumber gonad Anti-inflammatory peptides Lipopolysaccharide Pro-inflammatory cytokines Molecular docking
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2590157526000313
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