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Enhanced Kidney Targeting and Distribution of Tubuloids During Normothermic Perfusion

Tubuloids have become a promising tool for modeling and regenerating kidney disease, although their ability for integration and regeneration in vivo is not well documented. Here, we established, characterized, and compared human tubuloids using two optimized protocols: one involving prior isolation...

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Principais autores: Enrique Montagud-Marrahi, Adriana Rodriguez-Gonzalo, Rubén López-Aladid, Yosu Luque, Ruben Rabadán-Ros, Elena Cuadrado-Payan, Elisenda Bañón-Maneus, Jordi Rovira, Marta Lazo-Rodríguez, Oriol Aguilà, Carolt Arana, Ainhoa García-Busquets, Natalia Hierro, Thomas Prudhomme, Mireia Musquera, Yun Xia, Fritz Diekmann, Josep M. Campistol, Maria José Ramírez-Bajo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-09-01
Serier:Transplant International
Fag:
tubuloids
kidney regeneration
transplantation
cell therapy
normothermic perfusion
Online adgang:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14747/full
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