Screening of Acetylcholinesterase Inhibitors by Capillary Electrophoresis with Oriented-Immobilized Enzyme Microreactors Based on Gold Nanoparticles

A facial and efficient method for the screening of acetylcholinesterase (AChE) inhibitors by capillary electrophoresis was developed. Based on the specific affinity of concanavalin A (Con A) for binding to the glycosyl group of AChE, enzyme molecules were oriented-immobilized on the surface of gold...

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Principais autores:	Jian Zhang, Yuanyuan Li, Lin Chen, Zhihong Zheng, Chunye Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-12-01
Series:	Molecules
Assuntos:	capillary electrophoresis oriented-immobilized enzyme microreactor acetylcholinesterase gold nanoparticles enzyme inhibitor screening
Acceso en liña:	https://www.mdpi.com/1420-3049/29/1/118
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