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The Role of MicroRNAs in Aβ Deposition and Tau Phosphorylation in Alzheimer’s Disease

Alzheimer’s disease (AD), with main clinical features of progressive impairment in cognitive and behavioral functions, is the most common degenerative disease of the central nervous system. Recent evidence showed that microRNAs (miRNAs) played important roles in the pathological progression of AD. I...

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Main Authors: Juanjuan Zhao, Dongxu Yue, Ya Zhou, Li Jia, Hairong Wang, Mengmeng Guo, Hualin Xu, Chao Chen, Jidong Zhang, Lin Xu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Neurology
Subjects:
Alzheimer’s disease
microRNAs
amyloid-beta
amyloid precursor protein
Tau protein
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00342/full
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