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Transcellular metabolism of leukotriene A4 by rabbit blood cells: lack of relevant LTC4-synthase activity in rabbit platelets

The objective of this study was to determine the transcellular metabolism of leukotriene A4 by rabbit blood cells. mixed peripheral blood leukocyte preparations with and without platelets in a ratio of 1:40 were challenged with the Ca(2+)-ionophore A23187. 5-Lipoxygenase metabolites production was a...

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Autori principali: A Sala, T Testa, F Nobili, G Folco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 1997-04-01
Serie:Journal of Lipid Research
Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520372308
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