Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells

Abstract Background Dihydroartemisinin (DHA) has been shown to exert anticancer activity through iron-dependent reactive oxygen species (ROS) generation, which is similar to ferroptosis, a novel form of cell death. However, whether DHA causes ferroptosis in glioma cells and the potential regulatory...

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Xehetasun bibliografikoak

Egile Nagusiak:	Yibing Chen, Yanjun Mi, Xiaofei Zhang, Qian Ma, Yucen Song, Liwei Zhang, Dandan Wang, Jinliang Xing, Benxin Hou, Haolong Li, Huan Jin, Wei Du, Zhengzhi Zou
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2019-09-01
Saila:	Journal of Experimental & Clinical Cancer Research
Gaiak:	Dihydroartemisinin Ferroptosis GPX4 Endoplasmic reticulum stress HSPA5 Glioma
Sarrera elektronikoa:	http://link.springer.com/article/10.1186/s13046-019-1413-7
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