Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation

Despite combination antiretroviral therapy (cART), acquired immunodeficiency syndrome (AIDS), predominantly caused by the human immunodeficiency virus type 1 (HIV-1), remains incurable. The barrier to a cure lies in the virus' ability to establish a latent infection in HIV/AIDS patients. Unsurprisin...

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מידע ביבליוגרפי

Principais autores:	Maxime J. Jean, Tsuyoshi Hayashi, Huachao Huang, Justin Brennan, Sydney Simpson, Andrei Purmal, Katerina Gurova, Michael C. Keefer, James J. Kobie, Netty G. Santoso, Jian Zhu
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2017-10-01
סדרה:	Frontiers in Microbiology
נושאים:	human immunodeficiency virus (HIV) HIV latency latency-promoting agents (LPA) FACT complex curaxins
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fmicb.2017.02007/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!