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Lung EC-SOD Overexpression Prevents Hypoxia-Induced Platelet Activation and Lung Platelet Accumulation

Pulmonary hypertension (PH) is a progressive disease marked by pulmonary vascular remodeling and right ventricular failure. Inflammation and oxidative stress are critical in PH pathogenesis, with early pulmonary vascular inflammation preceding vascular remodeling. Extracellular superoxide dismutase...

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Principais autores: Daniel Colon Hidalgo, Mariah Jordan, Janelle N. Posey, Samuel D. Burciaga, Thi-Tina N. Nguyen, Christina Sul, Caitlin V. Lewis, Cassidy Delaney, Eva S. Nozik
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-08-01
Serier:Antioxidants
Fag:
platelets
pulmonary hypertension
superoxide dismutase
hypoxia
Online adgang:https://www.mdpi.com/2076-3921/13/8/975
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