Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Abstract Radiotherapy failure often arises from tumor repopulation by treatment‐resistant cancer cells. Following irradiation, cancer cells can undergo endoreplication to form polyploid giant cancer cells (PGCCs)—radiation‐persistent cells capable of generating progeny through a virus‐like asymmetri...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Wiley 2026-02-01
Sarja:	Advanced Science
Aiheet:	Budding Polyploid giant cancer cells Radio‐sensitization Radiotherapy Tumor repopulation
Linkit:	https://doi.org/10.1002/advs.202519698
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