Comparison of tumors with HER2 overexpression versus HER2 amplification in HER2-positive breast cancer patients

Abstract Background Human epidermal growth factor receptor 2 (HER2)-positive tumors are defined by protein overexpression (3+) or gene amplification using immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH), respectively. HER2-positive tumors have historically included both IHC(3...

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Autors principals:	Yoshiya Horimoto, Yumiko Ishizuka, Yuko Ueki, Toru Higuchi, Atsushi Arakawa, Mitsue Saito
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-03-01
Col·lecció:	BMC Cancer
Matèries:	Breast cancer HER2 Immunohistochemistry In situ hybridization Trastuzumab
Accés en línia:	https://doi.org/10.1186/s12885-022-09351-4
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