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A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole duplication and mitotic PCM recruitment. We analys...

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Auteurs principaux: Jeroen Dobbelaere, Filipe Josué, Saskia Suijkerbuijk, Buzz Baum, Nicolas Tapon, Jordan Raff
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2008-09-01
Collection:PLoS Biology
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18798690/?tool=EBI
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