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PCR-based detection of a rare linear DNA in cell culture

<p>The described method allows for detection of rare linear DNA fragments generated during genomic deletions. The predicted limit of the detection is one DNA molecule per 10<sup>7</sup> or more cells. The method is based on anchor PCR and involves gel separation of the linear DNA fragment and chromo...

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Detalles Bibliográficos
Autor principal: Saveliev Sergei V.
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2002-01-01
Colección:Biological Procedures Online
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Acceso en línea:http://www.biologicalprocedures.com/bpo/arts/1/36/m36.htm
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