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Role of the ATPase/helicase maleless (MLE) in the assembly, targeting, spreading and function of the male-specific lethal (MSL) complex of <it>Drosophila</it>

<p>Abstract</p> <p>Background</p> <p>The male-specific lethal (MSL) complex of <it>Drosophila </it>remodels the chromatin of the X chromosome in males to enhance the level of transcription of most X-linked genes, and thereby achieve dosage compensation. The core complex consists of five proteins and...

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Autori principali: Morra Rosa, Yokoyama Ruth, Ling Huiping, Lucchesi John C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2011-04-01
Serie:Epigenetics & Chromatin
Accesso online:http://www.epigeneticsandchromatin.com/content/4/1/6
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