AphA-dependent c-di-GMP production in Vibrio parahaemolyticus is mediated by direct regulation of eapA transcription encoding an EAL domain-containing protein

ABSTRACT Vibrio parahaemolyticus, a major seafood-borne pathogen, employs quorum sensing (QS) and c-di-GMP to regulate virulence, motility, and biofilm formation. While the master QS regulator AphA promotes c-di-GMP accumulation at low cell density (LCD), the underlying mechanism remained unclear. H...

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Hlavní autoři:	Nan Zhang, Wu Xu, Xue Li, Miaomiao Zhang, Xi Luo, Bin Ni, Renfei Lu, Yiquan Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-10-01
Edice:	Journal of Bacteriology
Témata:	V. parahaemolyticus AphA c-di-GMP biofilm formation motility regulation
On-line přístup:	https://journals.asm.org/doi/10.1128/jb.00104-25
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