Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma

Abstract Medullary thyroid carcinoma (MTC) is a rare, aggressive neuroendocrine tumor with limited treatment options and frequent recurrence. Comprehensive recurrence risk stratification remains lacking. Here, we profile 482 MTC samples from 452 patients across ten Chinese clinical centers, identify...

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Detalhes bibliográficos

Principais autores:	Yan Zhou, Yingrui Wang, Xiao Shi, Jiatong Wang, Zelin Zang, Likun Zhang, Zhiqiang Gui, Xue Cai, Pingping Hu, Jiaxi Wang, Hanqing Liu, Zhihong Wang, Haixia Guan, Xiaohong Wu, Cenkai Shen, Yi He, Mo Li, Hao Zhang, Jianbiao Wang, Yijun Wu, Chuang Chen, Yi Zhu, Yaoting Sun, Zhiyan Liu, Yu Wang, Tiannan Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-01-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-025-67533-7
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