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The spatial architecture of neuroimmune interactions in epilepsy

Epilepsy is increasingly recognized as a disorder not only of neuronal dysfunction but also of immune dysregulation within the central nervous system (CNS). Accumulating evidence points to a critical role for the immune microenvironment in shaping epileptogenesis—the process that underlies the devel...

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Main Authors: Dianwu Chu, Wuhao Zhang, Xing Zhou, Hang Yin, Jian Yin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-02-01
Series:Frontiers in Immunology
Subjects:
astrocyte
epilepsy
immune microenvironment
microglia
neuroinflammation
spatial transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1742927/full
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