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BRAF-MEK inhibitors as steroid-sparing bridge prior to checkpoint blockade therapy in symptomatic intracranial melanoma

The introduction of immune checkpoint blockade (ICB) and BRAF-MEK inhibitors has substantially improved outcomes in patients with metastatic melanoma. However, several challenging factors may hinder the efficacy of ICB in patients with symptomatic intracranial metastatic melanoma who are immunosuppr...

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Bibliografische gegevens
Hoofdauteurs: Karam Khaddour, Tanner M Johanns, George Ansstas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis Group 2021-06-01
Reeks:Melanoma Management
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Online toegang:https://www.futuremedicine.com/doi/10.2217/mmt-2020-0022
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