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Cellular senescence in brain aging and neurodegeneration: from molecular mechanisms to translational opportunities

Aging remains the predominant risk factor for Alzheimer’s disease (AD) and other neurodegenerative disorders, yet the mechanisms linking systemic aging to brain dysfunction remain incompletely understood. Cellular senescence, a state of stable cell-cycle arrest coupled with metabolic and secretory r...

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Autors principals: Yahveth Cantero-Fortiz, Christopher Butler, Xavier Montalbán, Mercè Boada
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-05-01
Col·lecció:Frontiers in Cellular Neuroscience
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fncel.2026.1805691/full
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