Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy
Abstract The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by mutations and chromosomal translocation in vital targets. The PI3K/AKT/mTOR signaling pathway is dysregulated in nearly all kinds of neoplasms, with the component in this pathway alternations. RAF/MEK/ERK signaling cascade...
Guardat en:
| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer
2022-12-01
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| Col·lecció: | Molecular Biomedicine |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s43556-022-00110-2 |
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