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Cysteine Mutants of the Major Facilitator Superfamily-Type Transporter CcoA Provide Insight into Copper Import

ABSTRACT CcoA belongs to the widely distributed bacterial copper (Cu) importer subfamily CalT (CcoA-like Transporters) of the Major Facilitator Superfamily (MFS) and provides cytoplasmic Cu needed for cbb3-type cytochrome c oxidase (cbb3-Cox) biogenesis. Earlier studies have supported a 12-transmemb...

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Principais autores: Bahia Khalfaoui-Hassani, Petru-Iulian Trasnea, Stefan Steimle, Hans-Georg Koch, Fevzi Daldal
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021-08-01
Serier:mBio
Fag:
copper uptake
cbb3-type cytochrome c oxidase
copper-binding residues
MFS-type transporters
Rhodobacter capsulatus CcoA
bacterial copper import
Online adgang:https://journals.asm.org/doi/10.1128/mBio.01567-21
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