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Expression of interferon-stimulated genes, but not polymorphisms in the interferon α/β receptor 2 gene, is associated with coronavirus disease 2019 mortality

Excessive inflammatory response is a hallmark of severe COVID-19. This study investigated the associations between interferon-stimulated genes (ISGs) expression, genetic variation in the interferon α/β receptor 2 (IFNAR2) gene, and COVID-19 mortality.We investigated 67 patients with moderate-to-seve...

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Hlavní autoři: Berliana Hamidah, Cennikon Pakpahan, Laksmi Wulandari, Damayanti Tinduh, Tri Wibawa, Cita Rosita Sigit Prakoeswa, Delvac Oceandy
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-10-01
Edice:Heliyon
Témata:
COVID-19
Interferon
Immune response
Interferon receptor
IFNAR2
Interferon type I
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2405844024150335
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