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An Efficient UPLC-MS/MS Method Established to Detect Relugolix Concentration in Rat Plasma

Relugolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist, has been well studied in the treatment of endometriosis symptomatic. It is mainly metabolized by the CYP3A subfamily of P450 enzymes, while minorly metabolized by CYP2C8. Daidzein in different dose groups exhibited a certain ind...

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Principais autores: Liying Xing, Ya-nan Liu, Hongye Yao, Tingting Wang, Fuchen Xie, Shunbin Luo, Pingping Luo, Shengling Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-06-01
Colecção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.874973/full
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