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Curcumin Prevents Epithelial-to Mesenchymal Transition-Mediated Ovarian Cancer Progression through NRF2/ETBR/ET-1 Axis and Preserves Mitochondria Biogenesis in Kidney after Cisplatin Administration

Purpose: Ovarian carcinoma is one of the gynaecological malignancies that have the highest mortality rates due to its progressivity. Endothelin signalling plays a leading role in the progression of ovarian cancer through Epithelial-to-Mesenchymal Transition (EMT). Cisplatin commonly used as potent c...

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Autores principales: Agian Jeffilano Barinda, Wawaimuli Arozal, Ni Made Dwi Sandhiutami, Melva Louisa, Nur Arfian, Normalina Sandora, Muhammad Yusuf
Formato: Artigo
Lenguaje:Inglês
Publicado: Tabriz University of Medical Sciences 2022-01-01
Colección:Advanced Pharmaceutical Bulletin
Materias:
ovarian cancer
curcumin
endothelin-1
etbr
nrf2
cisplatin-induced kidney injury
Acceso en línea:https://apb.tbzmed.ac.ir/PDF/apb-12-128.pdf
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