Computational design of a multi-epitope vaccine against Helicobacter pylori targeting CagA, FliD, urease, and OipA with cholera toxin B subunit (CTB) adjuvant

Abstract Background Helicobacter pylori, a Gram-negative, microaerophilic bacterium with a characteristic spiral morphology, inhabits the stomachs of approximately half of the world’s population. This study aimed to design a multi-epitope vaccine against H. pylori using immunoinformatics approaches,...

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Detalhes bibliográficos

Principais autores:	Najmeh Baniasadi Nejad, Behzad Shahbazi, Parisa Sarkoohi, Nahid Ahmadi, Khadijeh Ahmadi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	BMC Microbiology
Assuntos:	Helicobacter pylori Multi-epitope vaccine Molecular docking Molecular dynamics simulation CTB
Acesso em linha:	https://doi.org/10.1186/s12866-026-05078-5
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