Submitted for your consideration: potential advantages of a novel clinical trial design and initial patient reaction

In many circumstances, individuals do not respond identically to the same treatment. This phenomenon, which is called treatment response heterogeneity (TRH), appears to be present in treatments for many conditions, including obesity. Estimating the total amount of TRH, predicting an individual’s res...

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Bibliografiske detaljer

Principais autores:	Matthew Shane Loop, Alexis C. Frazier-Wood, Amy S. Thomas, Emily J. Dhurandhar, James M. Shikany, Gary L. Gadbury, David B Allison
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2012-08-01
Serier:	Frontiers in Genetics
Fag:	Balaam design crossover design Randomization treatment response heterogeneity non-responder
Online adgang:	http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00145/full
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