Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation

Abstract Avian influenza A viruses (IAVs) pose a public health threat, as they are capable of triggering pandemics by crossing species barriers. Replication of avian IAVs in mammalian cells is hindered by species-specific variation in acidic nuclear phosphoprotein 32 (ANP32) proteins, which are esse...

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Hlavní autoři:	Ecco Staller, Loïc Carrique, Olivia C. Swann, Haitian Fan, Jeremy R. Keown, Carol M. Sheppard, Wendy S. Barclay, Jonathan M. Grimes, Ervin Fodor
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-05-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-48470-3
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