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PFNA dominates the association between PFAS mixture exposure and hypertension risk: The mediating role of estradiol in the U.S. adults

This study aimed to investigate the association between per- and polyfluoroalkyl substances (PFAS) mixture exposure and hypertension risk, and to assess the mediating role of estradiol. We investigated these questions in 5175 adults from the U.S. National Health and Nutrition Examination Survey (NHA...

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Autori principali: Ling Li, Minqi Li, Jingwen Jiang, Jie Wang, Liwen Zhu, Na Jiang, Xingyang He, Hanlu Liu, Shan Wang, Jun He, Qinghai Zhang, Xiuqin Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-05-01
Serie:Ecotoxicology and Environmental Safety
Soggetti:
Per- and polyfluoroalkyl substances (PFAS)
Perfluorononanoic Acid (PFNA)
Hypertension
Estradiol
Mediation analysis
Mixture exposure
Accesso online:http://www.sciencedirect.com/science/article/pii/S0147651326004537
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