Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol for a double-blind randomized trial

Abstract Background Acute microcirculatory perfusion disturbances and organ edema are important factors leading to organ dysfunction during cardiac surgery with cardiopulmonary bypass (CPB). Priming of the CPB system with crystalloid or colloid fluids, which inevitably leads to hemodilution, could c...

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Hauptverfasser:	Anne M. Beukers, Carolien S. E. Bulte, Ruben J. Bosch, Susanne Eberl, Charissa E. van den Brom, Stephan A. Loer, Alexander B. A. Vonk
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-03-01
Schriftenreihe:	Trials
Schlagworte:	Cardiopulmonary bypass Priming Microcirculation Colloid Crystalloid Albumin
Online-Zugang:	https://doi.org/10.1186/s13063-024-08053-5
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