Notch Signaling Is Associated With ALDH Activity And An Aggressive Metastatic Phenotype In Murine Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone, and pulmonary metastatic disease accounts for nearly all mortality. However, little is known about the biochemical signaling alterations that drive the progression of metastatic disease. Two murine OS cell populations, K7M2 and K12, ar...

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Autors principals:	Xiaodong eMu, Christian eIsaac, Nicholas eGreco, Johnny eHuard, Kurt eWeiss
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2013-06-01
Col·lecció:	Frontiers in Oncology
Matèries:	Osteosarcoma metastasis cancer stem cells Notch ALDH
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00143/full
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