Degenerated human intervertebral discs contain autoantibodies against extracellular matrix proteins

Degeneration of intervertebral discs (IVDs) is associated with back pain and elevated levels of inflammatory cells. It has been hypothesised that discogenic pain is a direct result of vascular and neural ingrowth along annulus fissures, which may expose the avascular nucleus pulposus (NP) to the sys...

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Autors principals:	S Capossela, P Schläfli, A Bertolo, T Janner, BM Stadler, T Pötzel, M Baur, JV Stoyanov
Format:	Artigo
Idioma:	Inglês
Publicat:	Forum Multimedia Publishing LLC 2014-04-01
Col·lecció:	European Cells & Materials
Matèries:	nucleus pulposus annulus fibrosus Intervertebral disc extracellular matrix
Accés en línia:	http://www.ecmjournal.org/journal/papers/vol027/pdf/v027a18.pdf
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