Activation of Nuclear Factor Erythroid 2-Related Factor 2 Transcriptionally Upregulates Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Expression and Inhibits Ectopic Calcification in Mice

Calcification plays a key role in biological processes, and breakdown of the regulatory mechanism results in a pathological state such as ectopic calcification. We hypothesized that ENPP1, the enzyme that produces the calcification inhibitor pyrophosphate, is transcriptionally regulated by Nrf2, and...

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Ngā kaituhi matua:	Ida Tomomi, Hiroyuki Kanzaki, Miho Shimoyama, Syunnosuke Tohyama, Misao Ishikawa, Yuta Katsumata, Chihiro Arai, Satoshi Wada, Shugo Manase, Hiroshi Tomonari
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2024-07-01
Rangatū:	Antioxidants
Ngā marau:	ectopic calcification Nrf2 pyrophosphate (PPi) osteoblastic differentiation ENPP1 anti-oxidation
Urunga tuihono:	https://www.mdpi.com/2076-3921/13/8/896
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!