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Ursolic Acid Protects Neurons in Temporal Lobe Epilepsy and Cognitive Impairment by Repressing Inflammation and Oxidation

Temporal lobe epilepsy (TLE) is characterized as an impaired ability of learning and memory with periodic and unpredictable seizures. Status epilepticus (SE) is one of the main causes of TLE. Neuroinflammation and oxidative stress are directly involved in epileptogenesis and neurodegeneration, promo...

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Main Authors: Kun-mei Liu, Yue Huang, Pan-pan Wan, Yun-hua Lu, Ning Zhou, Juan-juan Li, Chun-yang Yu, Jin-jiang Chou, Lianxiang Zhang, Chun Zhang, Yuan-yuan Qiang, Rui Zhang, Le Guo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
temporal lobe epilepsy
cognitive impairment
ursolic acid
anti-inflammatory
antioxidant
neuroprotective
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.877898/full
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