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Optimization of apigenin nanoparticles prepared by planetary ball milling: In vitro and in vivo studies

This study intended to optimize apigenin (APG) nanoparticle formulation prepared by planetary ball milling to enhance its dissolution rate and bioavailability using a design of experiment (DoE). In this study, polyvinyl pyrrolidone (PVP K30) was used as a nanoparticle stabilizer. The independent par...

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Principais autores: Alshehri Abdulla Ali, Ibrahim Mohamed Abbas, Alshehri Sultan Mohamed, Alshora Doaa, Elzayat Ehab Mostafa, Almeanazel Osaid, Alsaadi Badr, El Sherbiny Gamal A., Osman Shaaban Khalaf
Formato: Artigo
Idioma:Inglês
Publicado em: De Gruyter 2023-02-01
coleção:Green Processing and Synthesis
Assuntos:
apigenin
optimization
nanonization
planetary ball milling
pharmacokinetics
Acesso em linha:https://doi.org/10.1515/gps-2022-8107
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