Harnessing γδ T cells for B7-H3-targeting CAR therapy to enhance anti-tumor therapy in glioblastoma
Abstract Background Glioblastoma (GBM) remains largely incurable, in part because the highly immunosuppressive tumor microenvironment (TME) poses a major barrier to conventional therapies, including to chimeric antigen receptor (CAR)-T cell therapy. Compared with conventional αβ T cells, γδ T cells...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMC
2026-03-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-026-07994-6 |
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