TRIM47 is a novel endothelial activation factor that aggravates lipopolysaccharide-induced acute lung injury in mice via K63-linked ubiquitination of TRAF2

Abstract Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we reported that TRIM47, an E3 ubiquitin ligase of the tripartite motif-containing protein family, was highly exp...

詳細記述

書誌詳細

主要な著者:	Yisong Qian, Ziwei Wang, Hongru Lin, Tianhua Lei, Zhou Zhou, Weilu Huang, Xuehan Wu, Li Zuo, Jie Wu, Yu Liu, Ling-Fang Wang, Xiao-Hui Guan, Ke-Yu Deng, Mingui Fu, Hong-Bo Xin
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2022-05-01
シリーズ:	Signal Transduction and Targeted Therapy
オンライン･アクセス:	https://doi.org/10.1038/s41392-022-00953-9
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!