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Dynamic changes of monocytes-related immune activation in people with HIV switching to long-acting injectable cabotegravir plus rilpivirine

Abstract The aim of this study was to examine the dynamic changes in monocyte/macrophage- and dendritic cell (DC)-related immune activation in people with HIV (PWH) before switching to long-acting (LA) injectable cabotegravir (CAB) plus rilpivirine (RPV) (T0), after six (T6m) and twelve months (T12m...

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Principais autores: Maria Antonella Zingaropoli, Mariasilvia Guardiani, Anna Carraro, Eeva Tortellini, Federica Dominelli, Michele Antonacci, Cosmo Del Borgo, Raffaella Marocco, Giulia Mancarella, Lorenzo Ansaldo, Piergiorgio Pace, Livia Bresciani, Serena Vita, Fabio Mengoni, Roberta Campagna, Ombretta Turriziani, Maria Rosa Ciardi, Claudio Mastroianni Mastroianni, Miriam Lichtner
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2026-03-01
Colecção:Scientific Reports
Assuntos:
Long-acting therapy
Cabotegravir
Rilpivirine
Monocytes
Dendritic cells, HIV-DNA, flow-cytometry
SCD163
Acesso em linha:https://doi.org/10.1038/s41598-026-44013-6
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